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Disease commences as a mild blood stream infection

Posted by Monica Wednesday, December 16, 2009

Hi guys. The disease commences as a mild blood stream infection and accordingly the clinical manifestations are gradual in onset and variable. The symptoms in order of free quench are sweating, weakness, headache, anorexia, pains in limbs and back, constipation, rigors, cough sore throat and joint pains. The spleen is palpable in about 20 per cent. Of cases and a variable rash occurs in about 10 per cent. The temperature characteristically shows undulations, during which febrile and afebrile periods alternate. In other cases the Pyrex may be continuous and sweating may be profuse. Untreated, the disease may last for a few days or continue for many moths, and in the latter case the patient often becomes extremely depressed or irritable. Neutropenia and lymphocytosis usually occur in the more severe case. Sub-acute arthritis of one or more joints may occur. The spine is often the site affected and occasionally radiological charges due to osteomyelitis of a verebra can be demonstrated. A paravertebral abscess, which is rare, may be distinguished from tuberculosis by the fact that there is less destruction of the intervertebral disc. The diagnosis of undulant fever can usually be confirmed by blood culture or by agglutination tests. Other conditions causing prolonged fever, such as tuberculosis, enteritis fever, and subacute bacterial endocarditis must be considered in differential diagnosis. Thanks guys.

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